WTF? Depression as a Neurochemical Glitch

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About Black and Blue Man

Black and Blue Man is a blogger in Australia "living with depression one day at a time at one hour at a time." Find him on his blog here.


  1. Thank you- you’ve just put exactly how I feel into words and made me realise that it’s the chemicals and not me being a selfish jerk by feeling like this.

  2. This is exactly how I feel at times. But it wasn’t until I had a conversation with a good friend a week ago about how I couldn’t focus at work that I realised I might be depressed.

    I took my first antidepressant this morning. Fingers crossed.

    • Back in mid-2007, I was nervous when my psychiatrist advised a course of medication – but in conjunction with weekly therapy, anti-depressants helped to improve my life greatly.

      All the best with your treatment.

  3. Cakethief says:

    I have the same feelings that come randomly through the day. It is a home sick feeling even when I’m home..really weird. Good to know I’m not alone, thanks for sharing.

  4. Thanks for this post, which brings up a number of good points. First, you don’t have to be at death’s door or ‘qualified’ within the DSM-IV to feel badly. Little clouds count even if they do not clobber to the point of incapacitation. Second, sometimes you do just have to keep on keepin’ on when there is no psychodynamic, behavioral, or physiologically known or knowable reason. “Sh*t happens” matters in neurology as well. Third, you stared down the self-hate monster. Perhaps some part of you was aware that self-hate is a symptom, not a reality. Fourth and perhaps most interesting from my standpoint, you noted that your spirits lifted after being unable to sleep. A few years ago there was literature floating around about ‘resetting’ depression by denying sleep. I do not know where this work went and surely do not think anyone should try this at home, kids. Yet the idea that there might be one more arrow in the self help quiver (such as ‘stay up and read a thriller’ or ‘go biking at night’) intrigues me.
    Thanks for your brave self disclosure.

  5. It’s often oddly reassuring when I’m feeling down to think “oh yeah, I”m seriously mentally ill, thats why I randomly feel like crap”

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