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Those impacted by Alzheimer’s disease (AD) will recognize it as a form of dementia that affects more than just a loved one’s memory. It is characterized by unfortunate cognitive decline and even changes to one’s personality.
Alzheimer’s disease can be divided into two distinct camps: late and early-onset. While the symptoms of each are similar, the difference lies in when the disease first begins to take effect. In more common cases, AD begins to appear after the mid-60s, however, earlier cases can begin as young as a person’s early 30s. This leads many to wonder, is Alzheimer’s genetic?
Current studies are inconclusive as to a single exact cause of AD, however, the cause for many could be due to genetics. Families who experience early-onset cases often show a pattern called autosomal dominant inheritance. This simply means that the disease could be passed from parent to child, with children of affected parents having a 50% chance of receiving this gene.
Non-genetic factors such as age, exercise level, diet, and activities that promote the health of the brain and the heart play a role in the development of Alzheimer’s. Researchers are seeking to improve the understanding of the connection between both genetic and non-genetic factors, how to reduce risk, and how to slow the progression of symptoms.
Can You Inherit Alzheimer’s Disease
Family members watching a loved one struggle with AD may wonder, is Alzheimer’s genetic? Studies suggest that AD does have a genetic component. But while certain variants can be associated with increased risks of developing this disease, they are far from the only factor. Many who suffer from AD do not possess genetics commonly associated with the disease. Others who do possess these genes never develop symptoms of AD. Genetic mutations may play a factor, but they don’t necessarily tell the whole story.
Does Alzheimer’s run in families?
The simple answer is that yes, AD can run in families under certain conditions. This is more often seen in cases of early onset. Those with a close relative who has developed AD are also more likely to suffer from it, though that is certainly not a guarantee one will develop this disease. Research even suggests that, while genetics are a factor, different lifestyles and diets can affect risk levels. Those who practice a healthier lifestyle, including diet and activity, may reduce their risks of developing AD later in life.
What are other risk factors for Alzheimer’s disease?
Non-genetic factors that are associated with higher or lower risk for Alzheimer’s. Many of them are interrelated and include diet, exercise, and heart health.
Most people diagnosed are over the age of 65 as the risk of Alzheimer’s increases as a person ages. Females are also more likely than males to develop late-onset Alzheimer’s. Family history can play a role, as can diet and heart health. However, research shows that exercise and less education have been associated with a greater risk of developing AD. Certain ethnic groups, such as African Americans and Hispanic/Latin Americans, have a higher likelihood of experiencing this condition compared to individuals from other racial and ethnic backgrounds.
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